技术发明人


 
 
黄波,载药囊泡治疗肿瘤技术发明人
教授,博士生导师
医学分子生物学国家重点实验室
中国医学科学院基础医学研究所/北京协和医学院
       
       黄波,中国医学科学院基础医学研究所&北京协和医学院“协和学者”特聘教授,博士生导师,同时系华中科技大学同济医学院生物化学与分子生物学系教授、博导。现任中国医学科学院基础医学研究所副所(院)长,北京协和医学院免疫学系副主任,中国免疫学会副秘书长,中国免疫学会常务理事以及中国生物化学与分子生物学会理事,中国抗癌协会肿瘤生物治疗专业委员会秘书长,中国免疫学会肿瘤生物治疗专业委员会主任委员,并担任Cellular Molecular Immunology、European Journal of Immunology、Cancer Letters等杂志的编委。
      黄波教授先后获得首届“中国免疫学青年学者奖”、“教育部新世纪优秀人才支持计划”资助、“湖北省有突出贡献的中青年专家”称号、“国家杰出青年基金”资助、“国家百千万人才和有突出贡献中青年专家”称号,并入选国家万人计划。2014年入选教育部“长江学者特聘教授”。
      黄波教授主要致力于肿瘤免疫、肿瘤生物治疗等前沿医学研究,在科研领域成绩斐然,作为通迅作者在国际知名学术期刊发表60余篇论文,包括Nature Materials、Cancer Cell、Nature Cell Biology、nature communications等,总引用次数达2000余次。
 
 
黄波教授代表论文
 
  • Liu J, Tan Y, Zhang H, Zhang Y, Xu P, Chen J, Poh YC, Tang K, Wang N, Huang B*. Soft fibrin gels promote selection and growth of tumorigenic cells. Nat Mater. 2012 Jul 1;11(8):734-41. (IF: 39.737)
 
  • Liu Y, Liang X, Dong W, Fang Y, Lv J, Zhang T, Fiskesund R, Xie J, Liu J, Yin X, Jin X, Chen D, Tang K, Ma J, Zhang H, Yu J, Yan J, Liang H, Mo S, Cheng F, Zhou Y, Zhang H, Wang J, Li J, Chen Y, Cui B, Hu ZW, Cao X, Qin FX, Huang B*. Tumor repopulating cells induce PD-1 expression in CD8+ T cells by transferring kynurenine and AhR activation. Cancer Cell. 2018 Mar 12;33(3):480-494. (IF: 27.407)
 
  • Li K, Wang F, Cao WB, Lv XX, Hua F, Cui B, Yu JJ, Zhang XW, Shang S, Liu SS, Yu JM, Han MZ, Huang B, Zhang TT, Li X, Jiang JD, Hu ZW. TRIB3 promotes APL progression through stabilization of the oncoprotein PML-RARα and inhibition of p53-mediated senescence. Cancer Cell. 2017 May 8;31(5):697-710. (IF: 27.407)
 
  • Liu Y, Gu Y, Han Y, Zhang Q, Jiang Z, Zhang X, Huang B, Xu X, Zheng J, Cao X. Tumor exosomal rnas promote lung pre-metastatic niche formation by activating alveolar epithelial TLR3 to recruit neutrophils. Cancer Cell. 2016 Aug 8;30(2):243-256. (IF: 27.407)
 
  • Ma R, Ji T, Zhang H, Dong W, Chen X, Xu P, Chen D, Liang X, Yin X, Liu Y, Ma J, Tang K, Zhang Y, Peng Y, Lu J, Zhang Y, Qin X, Cao X, Wan Y, Huang B*. A Pck1-directed glycogen metabolic program regulates formation and maintenance of memory CD8+ T cells. Nat Cell Biol. 2018 Jan;20(1):21-27.(IF: 20.060)
 
  • Ma J, Zhang Y, Tang K, Zhang H, Yin X, Li Y, Xu P, Sun Y, Ma R, Ji T, Chen J, Zhang S, Zhang T, Luo S, Jin Y, Luo X, Li C, Gong H, Long Z, Lu J, Hu Z, Cao X, Wang N, Yang X, Huang B*. Reversing drug resistance of soft tumor-repopulating cells by tumor cell-derived chemotherapeutic microparticles. Cell Res2016 Jun;26(6):713-27.(IF=15.606)
 
  • Liu Y, Lv J, Liu J, Liang X, Jin X, Xie J, Zhang L, Chen D, Fiskesund R, Tang K, Ma J, Zhang H, Dong W, Mo S, Zhang T, Cheng F, Zhou Y, Jia Q, Zhu B, Kong Y, Guo J, Zhang H, Hu ZW, Cao X, Qin FX, Huang B*. STAT3/p53 pathway activation disrupts IFN-β-induced dormancy in tumor-repopulating cells. J Clin Invest. 2018 Mar 1;128(3):1057-1073. (IF: 12.784)
 
  • Tang K, Zhang Y, Zhang H, Xu P, Liu J, Ma J, Lv M, Li D, Katirai F, Shen GX, Zhang G, Feng ZH, Ye D, Huang B*. Delivery of chemotherapeutic drugs in tumour cell-derived microparticles. Nat Commun. 2012;3:1282. (IF: 12.124)
 
  • Chen D, Xie J, Fiskesund R, Dong W, Liang X, Lv J, Jin X, Liu J, Mo S, Zhang T, Cheng F, Zhou Y, Zhang H, Tang K, Ma J, Liu Y, Huang B*. Chloroquine modulates antitumor immune response by resetting tumor-associated macrophages towards M1 phenotype.Nat Commun. 2018 Feb 28;9(1):873. (IF: 12.124)
 
  • Hua F, Li K, Yu JJ, Lv XX, Yan J, Zhang XW, Sun W, Lin H, Shang S, Wang F, Cui B, Mu R, Huang B, Jiang JD, Hu ZW*. TRB3 links insulin/IGF to tumour promotion by interacting with p62 and impeding autophagic/ proteasomal degradations. Nat Commun. 2015, 13;6:7951. (IF: 12.124)
 
 
 
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